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Blood clots in the liver or kidney can cause sudden, intense pain. Treatment goals for patients with polycythemia are to manage symptoms and reduce the risk of complications like heart attack and stroke. Some genetic disorders are inherited from the parents, while other genetic diseases are caused by acquired changes or mutations in a preexisting gene or group of genes.Mutations can occur either randomly or due to some environmental exposure.Abnormalities in chromosomes typically occur due to a problem with cell division.For example, Down syndrome (sometimes referred to as "Down's syndrome") or trisomy 21 is a common disorder that occurs when a person has three copies of chromosome 21.Examples of multifactorial inheritance include: Chromosomes, distinct structures made up of DNA and protein, are located in the nucleus of each cell.
This type of inheritance is caused by changes or mutations that occur in the DNA sequence of a single gene.
For example, different genes that influencebreast cancer susceptibility have been found on chromosomes 6, 11, 13, 14, 15, 17, and 22.
Some common chronic diseases are multifactorial disorders.
Genetics is the study of the pattern of inheritance.
A geneticist studies birth disorders and their cause.
Some examples of monogenetic disorders include: Multifactorial inheritance, which is also called complex or polygenic inheritance.